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Rubella embryopathy: Symptoms, Cause and Treatment

Embryopathy is a a morbid condition of the embryo or a disorder resulting from abnormal embryonic development, with consequent congenital anomalies.

An infant born to a mother who had had rubella in early pregnancy exhibited cataract and congenital heart disease as typical features of a rubella embryopathy but had in addition purpura on the basis of a hypoplastic thrombocytopenia.

Prevention of rubella embryopathy

Early diagnosis is essential for the protection of pregnant hospital personnel, since the affected infant is able to harbor and transmit the rubella virus.

Currently, all developed countries include rubella vaccination in their immunization programs, targeting the complete elimination of congenital rubella syndrome (CRS). In the underdeveloped world, where this severely disabling condition still exists, only a few countries have implemented vaccination policies, and almost no data on their effectiveness or on prevalence rates are available.

Diagnosis of rubella embryopathy

The diagnosis of rubella embryopathy was confirmed by demonstrating rubella-specific serum IgM antibodies using four different methods, by the persistence of rubella HAI and IgG antibodies in serum taken between three and eight months of age and by the isolation of rubella virus from throat secretion, urine and blood mononuclear cells.


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